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产品目录

重组人ACE2(Fc标签)图片
产品货号:
JN2061
中文名称:
重组人ACE2(Fc标签)
英文名称:
Recombinant Human ACE-2 (C-Fc)
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a Fc tag at the C-terminus.

制剂:Lyophilized from a 0.2μm filtered solution of 20mM Tris-HCl,300mM NaCl,1mM ZnCl2,10% Glycerol,pH7.4.
纯度:>95% as determined by reducing SDS-PAGE.
内毒素:<0.1ng/μg (1 EU/μg) as determined by LAL test.
生物活性:

Immobilized Human ACE-2(Fc Tag)(Cat#JN2061) at 10μg/ml (100μl/well) can bind SARS-CoV-2 S Protein RBD-SD1-mFc(Cat#JN2088).The ED50of Recombinant SARS-CoV-2 S Protein RBD-mFc(Cat#JN2088) is 15.5ng/ml。

保存条件:-20℃,有效期6个月,避免反复冻融。

背景资料:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family,the ACE family includes somatic and germinal ACE.ACE-2 cleaves angiotensins I and II as a carboxypeptidase,ACE-2 converts angiotensin I to angiotensin 1-9,and angiotensin II to angiotensin 1-7.ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency.ACE-2 can be high expressed in testis,kidney and heart,in colon,small intestine and ovary at moderate levels.Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity.ACE-2 may play an important role in regulating the heart function.
相关搜索:重组人ACE2(Fc标签)重组人ACE-2重组人血管紧张素转换酶2重组人血管紧张素转化酶2Recombinant Human ACE-2 (C-Fc)
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